Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660567 | 1.00 | METAP2 (0.46) | METAP2METAP1IDO1GAAL3MBTL1 | |
| SCHEMBL12927229 | 1.00 | METAP2 (0.46) | METAP2METAP1IDO1GAAL3MBTL1 | |
| SCHEMBL28672429 | 1.00 | METAP2 (0.46) | METAP2METAP1IDO1GAAL3MBTL1 | |
| SCHEMBL9009370 | 1.00 | METAP2 (0.46) | METAP2METAP1IDO1GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9009360 | 0.98 | IDO1 (0.46) | METAP2METAP1IDO1GAAL3MBTL1 | |
| SCHEMBL10349212 | 0.98 | METAP2 (0.43) | METAP2METAP1IDO1GAAL3MBTL1 | |
| SCHEMBL6854233 | 0.90 | SCN4A (0.44) | IDO1SCN4A | |
| SCHEMBL3061093 | 0.90 | SCN4A (0.44) | IDO1SCN4A | |
| SCHEMBL5455701 | 0.90 | SCN4A (0.44) | IDO1SCN4A | |
| SCHEMBL17892144 | 0.87 | CHRNB2 (0.43) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37035-E1 | HYPOGLYCEMIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-30 | — | — | US | disclosed |
| US-6143769-A | ENANTIOMORPH | KARL THOMAE GMBH (DE) | 2000-11-07 | — | — | US | disclosed |
| US-5312924-A | Compounds for lowering blood sugar and effecting metabolism | DR. KARL THOMAE GMBH (DE) | 1994-05-17 | — | — | US | disclosed |
| US-5216167-A | Hypoglycemic agents | DR. KARL THOMAE GMBH (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0208200-A1 | Phenylacetic-acid derivatives, pharmaceutical compositions containing them and processes for their production | Dr. Karl Thomae GmbH (DE) | 1987-01-14 | — | — | EP | disclosed |