Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783673 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4EMEN1MAPT | |
| SCHEMBL2783264 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1HSD17B10KDM4EMEN1MAPT | |
| SCHEMBL2784631 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1HSD17B10KDM4EMEN1MAPT | |
| SCHEMBL2785174 | 0.85 | SMN1; SMN2 (0.49) | ALDH1A1HSD17B10KDM4EMEN1MAPT | |
| SCHEMBL2782955 | 0.85 | SMN1; SMN2 (0.49) | ALDH1A1HSD17B10KDM4EMEN1MAPT | |
| SCHEMBL2784727 | 0.85 | SMN1; SMN2 (0.55) | ALDH1A1HSD17B10KDM4EMEN1MAPT | |
| SCHEMBL2786584 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4EMEN1MAPT | |
| SCHEMBL2783353 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4EMEN1MAPT | |
| SCHEMBL2784017 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1HSD17B10KDM4EMEN1MAPT | |
| SCHEMBL2784057 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1HSD17B10KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085237-A1 | Fluorinated Diamine and Polymer Formed Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2013-04-04 | — | — | US | disclosed |
| US-20100029895-A1 | Fluorinated Diamine and Polymer Formed Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029895-A1 | Fluorinated Diamine and Polymer Formed Therefrom | AFF2, AFF1, AFF4 | ALDH1A1 931/4885HSD17B10 3598/4885KDM4E 1841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.