Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2782955 | 0.93 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2785908 | 0.87 | KDM4E (0.49) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2784727 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2783673 | 0.85 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2783773 | 0.85 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2784209 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2783169 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL1635164 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL12724450 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2783559 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085237-A1 | Fluorinated Diamine and Polymer Formed Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2013-04-04 | — | — | US | disclosed |
| US-20100029895-A1 | Fluorinated Diamine and Polymer Formed Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029895-A1 | Fluorinated Diamine and Polymer Formed Therefrom | AFF2, AFF1, AFF4 | SMN1; SMN2 3673/4885MEN1 2546/4885KMT2A 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.