Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049212 | 0.83 | HSD17B10 (0.46) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL2049214 | 0.83 | HSD17B10 (0.46) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL1019524 | 0.77 | ERN1 (0.69) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL15099833 | 0.77 | ALDH1A1 (0.50) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL705623 | 0.76 | TDP1 (0.60) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL3209275 | 0.76 | TYR (0.52) | ALDH1A1MEN1KMT2AMAPTTTR | |
| SCHEMBL11407699 | 0.76 | ERN1 (0.67) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL10774187 | 0.74 | CYP3A4 (0.43) | HSD17B10ALDH1A1CYP3A4TDP1MAPK1 | |
| SCHEMBL7372197 | 0.74 | TSHR (0.49) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL7372200 | 0.74 | TSHR (0.49) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102245587-A | Trpv1 antagonists | ABBOTT LAB | 2011-11-16 | — | — | CN | disclosed |
| CN-102186836-A | Trpv1 antagonists | ABBOTT LAB | 2011-09-14 | — | — | CN | disclosed |