Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68762 | 0.81 | TYR (0.59) | TYRTTRSYNJ2CYP1A1BCHE | |
| SCHEMBL9743148 | 0.81 | TYR (0.59) | TYRTTRSYNJ2CYP1A1BCHE | |
| SCHEMBL68761 | 0.81 | TYR (0.59) | TYRTTRSYNJ2CYP1A1BCHE | |
| SCHEMBL7599839 | 0.80 | ALDH1A1 (0.48) | TYRMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL1822010 | 0.79 | TYR (0.75) | TYRTTRSYNJ2CYP1A1BCHE | |
| SCHEMBL1822012 | 0.79 | TYR (0.75) | TYRTTRSYNJ2CYP1A1BCHE | |
| SCHEMBL3210928 | 0.78 | TRIM24 (0.69) | TYRCYP1A1PTGS1CYP1B1MEN1 | |
| SCHEMBL27796096 | 0.76 | CA3 (0.50) | TYRALOX5PTGS1AMY1A | |
| SCHEMBL27837751 | 0.76 | HSD17B10 (0.50) | TTRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27809742 | 0.76 | ERN1 (0.47) | MEN1KMT2APOLBMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937090-B2 | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO COMPANY, LTD. (JP) | 2015-01-20 | — | — | US | disclosed |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | SHISEIDO COMPANY, LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-1941861-A1 | WRINKLE-IMPROVING AGENT | Shiseido Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-1880711-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
| CN-1918160-A | Novel tricyclic spiroderivatives as modulators of chemokine receptor activity | ASTRAZENECA AB (SE) | 2007-02-21 | — | — | CN | disclosed |
| US-6537410-B2 | Thermal transfer recording system | POLAROID CORPORATION | 2003-03-25 | — | — | US | disclosed |
| EP-1263607-A1 | THERMAL TRANSFER RECORDING SYSTEM HAVING AN AMORPHOUS DYE PHASE | POLAROID CORPORATION (US) | 2002-12-11 | — | — | EP | disclosed |
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-20010043239-A1 | Thermal transfer recording system | MOROOD INTERNATIONAL, SPC (SA) | 2001-11-22 | — | — | US | disclosed |
| WO-2001056805-A1 | THERMAL TRANSFER RECORDING SYSTEM HAVING AN AMORPHOUS DYE PHASE | POLAROID CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | TYR 84/4885TTR 821/4885SYNJ2 3640/4885 |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | CUTA, AAAS, NUP160 | TYR 108/4885TTR 464/4885SYNJ2 4027/4885 |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | TYR 86/4885TTR 364/4885SYNJ2 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.