Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783518 | 0.88 | MAOB (0.51) | MAOBL3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL2785343 | 0.86 | MAOB (0.49) | MAOBL3MBTL1MRGPRX4ALDH1A1NPC1 | |
| SCHEMBL2784267 | 0.81 | MAOB (0.61) | MAOBHPGDALDH1A1NPC1MAPT | |
| SCHEMBL10751852 | 0.77 | MAOB (0.72) | MAOBHPGDALDH1A1NPC1MAPT | |
| SCHEMBL9819174 | 0.70 | AKR1B1 (0.56) | MAOBHPGDAKR1B1MRGPRX4ALDH1A1 | |
| SCHEMBL2786854 | 0.69 | MAOB (0.49) | MAOBL3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL2784548 | 0.68 | MAOB (0.47) | MAOBL3MBTL1MRGPRX4ALDH1A1NPC1 | |
| SCHEMBL4726898 | 0.67 | MAOB (1.00) | MAOBHPGDALDH1A1NPC1MAPT | |
| SCHEMBL6604268 | 0.67 | MAOB (0.82) | MAOBHPGDALDH1A1NPC1MAPT | |
| SCHEMBL3612372 | 0.65 | NPC1 (0.49) | MAOBHPGDPPARGL3MBTL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128038-A1 | HYDROQUINONE DERIVATIVES | AXOGLIA THERAPEUTICS S.A. (LU) | 2010-11-11 | — | — | WO | disclosed |