Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783518 | 0.87 | MAOB (0.51) | MAOBL3MBTL1NPC1ALDH1A1MAPT | |
| SCHEMBL2783803 | 0.86 | MAOB (0.50) | MAOBL3MBTL1MRGPRX4NPC1ALDH1A1 | |
| SCHEMBL2784548 | 0.82 | MAOB (0.47) | MAOBRXRARXRBRXRGL3MBTL1 | |
| SCHEMBL2784267 | 0.81 | MAOB (0.61) | MAOBNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL10751852 | 0.76 | MAOB (0.72) | MAOBNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL2786854 | 0.69 | MAOB (0.49) | MAOBL3MBTL1NPC1ALDH1A1MAPT | |
| SCHEMBL4770022 | 0.66 | ALOX5AP (0.46) | MAOBRXRARXRBRXRGL3MBTL1 | |
| SCHEMBL4726898 | 0.66 | MAOB (1.00) | MAOBNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL6604268 | 0.66 | MAOB (0.82) | MAOBNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL18587451 | 0.66 | RXRA (0.53) | RXRARXRBRXRGL3MBTL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128038-A1 | HYDROQUINONE DERIVATIVES | AXOGLIA THERAPEUTICS S.A. (LU) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128514-A1 | AMINO ACID PERHYDRATES, PROCESS FOR THEIR PREPARATION AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD (IL) | 2010-11-11 | — | — | WO | disclosed |