Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786854 | 0.88 | MAOB (0.49) | MAOBL3MBTL1NPC1ALDH1A1MAPT | |
| SCHEMBL2785343 | 0.82 | MAOB (0.49) | MAOBRXRARXRBRXRGALOX5AP | |
| SCHEMBL2784597 | 0.81 | MAOB (0.59) | MAOBNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL2784759 | 0.78 | CYP1A1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL10751852 | 0.75 | MAOB (0.72) | MAOBNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL8798562 | 0.71 | ATM (0.44) | MAOBL3MBTL1NPC1ALDH1A1MAPT | |
| SCHEMBL2783959 | 0.70 | MAPT (0.63) | ALDH1A1MAPT | |
| SCHEMBL2784581 | 0.69 | KDM4E (0.39) | ALDH1A1MAPT | |
| SCHEMBL2783518 | 0.69 | MAOB (0.51) | MAOBL3MBTL1NPC1ALDH1A1MAPT | |
| SCHEMBL8800839 | 0.68 | MAPT (0.37) | MAOBL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128038-A1 | HYDROQUINONE DERIVATIVES | AXOGLIA THERAPEUTICS S.A. (LU) | 2010-11-11 | — | — | WO | disclosed |