Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 10/20 | 0.60 |
| ▸ | MMP12 | P39900 | 4/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783859 | 1.00 | BMP1 (0.60) | BMP1MMP12DPP4DPP9ALDH1A1 | |
| SCHEMBL1596230 | 0.85 | BMP1 (0.65) | BMP1MMP12DPP4DPP9ALDH1A1 | |
| SCHEMBL4583761 | 0.85 | BMP1 (0.65) | BMP1MMP12DPP4DPP9ALDH1A1 | |
| SCHEMBL1596233 | 0.85 | BMP1 (0.65) | BMP1MMP12DPP4DPP9ALDH1A1 | |
| SCHEMBL4958420 | 0.75 | TSHR (0.43) | HPGDKMT2A | |
| SCHEMBL4592397 | 0.75 | TSHR (0.43) | HPGDKMT2A | |
| SCHEMBL1596984 | 0.72 | ALDH1A1 (0.47) | BMP1MMP12ALDH1A1HPGD | |
| SCHEMBL1596978 | 0.72 | ALDH1A1 (0.47) | BMP1MMP12ALDH1A1HPGD | |
| SCHEMBL1596987 | 0.72 | ALDH1A1 (0.47) | BMP1MMP12ALDH1A1HPGD | |
| SCHEMBL6023714 | 0.69 | BMP1 (0.62) | BMP1MMP12ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4563798-B2 | — | — | 2010-10-13 | — | — | JP | claimed |
| EP-1509218-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-03-26 | — | — | EP | claimed |
| EP-1509218-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003101442-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | claimed |
| EP-1509218-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1827449-A4 | THE USE OF NOVEL ANTIBACTERIAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-01-23 | — | — | EP | disclosed |
| EP-1827449-A2 | THE USE OF NOVEL ANTIBACTERIAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006055663-A2 | THE USE OF NOVEL ANTIBACTERIAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-05-26 | — | — | WO | disclosed |
| EP-1509218-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101442-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |