Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25504694 | 0.90 | ADORA1 (0.41) | ADORA1POLBPRMT6KDM4E | |
| SCHEMBL18848394 | 0.90 | P2RY12 (0.41) | ADORA1 | |
| SCHEMBL18848392 | 0.90 | ADORA1 (0.39) | ADORA1POLBPRMT6ADORA3ADORA2A | |
| SCHEMBL31629565 | 0.87 | POLB (0.49) | ADORA1POLB | |
| SCHEMBL25505318 | 0.85 | PRMT6 (0.39) | ADORA1PRMT6 | |
| SCHEMBL12582481 | 0.85 | PRMT6 (0.38) | ADORA1PRMT6ADORA3 | |
| SCHEMBL25748695 | 0.84 | PRMT6 (0.47) | ADORA1PRMT6ADORA3ADORA2AADORA2B | |
| SCHEMBL20534948 | 0.84 | POLB (0.51) | ADORA1POLBPRMT6 | |
| SCHEMBL11049246 | 0.84 | POLB (0.51) | ADORA1POLBPRMT6 | |
| SCHEMBL19519648 | 0.83 | POLB (0.61) | ADORA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024776-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-03-01 | — | — | WO | disclosed |