Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1320504 | 0.86 | RXFP1 (0.40) | LMNAPOLBRXFP1BRD9KMT2A | |
| SCHEMBL30793049 | 0.86 | RXFP1 (0.43) | LMNAPOLBRXFP1BRD9KMT2A | |
| SCHEMBL22735089 | 0.83 | LMNA (0.47) | LMNAPOLBRXFP1BRD9KMT2A | |
| SCHEMBL29991357 | 0.83 | KMT2A (0.59) | LMNAPOLBKMT2AL3MBTL1PDK1 | |
| SCHEMBL729221 | 0.83 | KMT2A (0.59) | LMNAPOLBKMT2AL3MBTL1PDK1 | |
| SCHEMBL2061241 | 0.82 | LMNA (0.50) | LMNAPOLBRXFP1BRD9KMT2A | |
| SCHEMBL2880191 | 0.82 | LMNA (0.54) | LMNAPOLBRXFP1BRD9KMT2A | |
| SCHEMBL7721814 | 0.81 | LMNA (0.55) | LMNAPOLBKMT2AL3MBTL1PDK1 | |
| SCHEMBL15060256 | 0.81 | LMNA (0.46) | LMNAPOLBRXFP1BRD9KMT2A | |
| SCHEMBL31604225 | 0.80 | GAA (0.39) | RXFP1BRD9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762226-A | Benzonaphthyridine-containing vaccines | NOVARTIS AG | 2012-10-31 | — | — | CN | disclosed |
| CN-102015651-A | Compounds and compositions as TLR activity modulators | IRM LLC | 2011-04-13 | — | — | CN | disclosed |