Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10169253 | 0.86 | ALDH1A1 (0.87) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL14846579 | 0.85 | HPGD (0.69) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL19178966 | 0.85 | HPGD (0.69) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL1104737 | 0.84 | ALDH1A1 (0.90) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL31721651 | 0.83 | ALDH1A1 (0.70) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7132525 | 0.82 | HPGD (1.00) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL27479149 | 0.82 | HPGD (1.00) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL10169258 | 0.81 | ALDH1A1 (0.96) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL27839734 | 0.81 | HPGD (0.62) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL13144177 | 0.81 | HPGD (0.62) | HPGDALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365280-B | adenosine receptor ligands and uses thereof | DOMAIN THERAPEUTICS (FR) | 2014-10-29 | — | — | CN | disclosed |
| CN-102365280-A | Novel adenosine receptor ligands and uses thereof | DOMAIN THERAPEUTICS | 2012-02-29 | — | — | CN | disclosed |