SCHEMBL27839986

SCHEMBL27839986

CCc1cccc(CC)c1NC.[LiH]

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 4/20 0.55
KCNH2 Q12809 2/20 0.55
GABRA1 P14867 4/20 0.48
GABRB2 P47870 4/20 0.48
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
HIF1A Q16665 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CACNA1C Q13936 3/20 0.44
CLCN2 P51788 1/20 0.43
NLRP3 Q96P20 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7196230 0.97 SCN5A (0.57) SCN5AKCNH2GABRA1GABRB2ALOX15
Hydrochloric Acid SCHEMBL2864438 0.95 SCN5A (0.55) SCN5AKCNH2GABRA1GABRB2ALOX15
SCHEMBL2868352 0.84 SCN5A (0.50) SCN5AKCNH2GABRA1GABRB2ALOX15
SCHEMBL11413705 0.82 GABRA1 (0.52) SCN5AKCNH2GABRA1GABRB2ALOX15
Hydrochloric Acid SCHEMBL2868350 0.82 PTGS2 (0.49) SCN5AKCNH2GABRA1GABRB2ALOX15
SCHEMBL11660113 0.82 KCNH2 (0.49) SCN5AKCNH2GABRA1GABRB2ALOX15
SCHEMBL11660568 0.82 SCN5A (0.49) SCN5AKCNH2GABRA1GABRB2ALOX15
SCHEMBL28429126 0.79 SCN5A (0.59) SCN5AKCNH2GABRA1GABRB2ALOX15
SCHEMBL23562240 0.79 SMN1; SMN2 (0.46) SCN5AKCNH2GABRA1GABRB2ALOX15
SCHEMBL949396 0.79 CHRM2 (0.47) SCN5AKCNH2CACNA1CKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102161682-A Non-bridged N-substituted aryllamino mono-titanocene compound and application thereof UNIV JILIN 2011-08-24 CN disclosed