Ganciclovir

Ganciclovir

SCHEMBL27842151

CO.Nc1nc2c(ncn2COC(CO)CO)c(=O)[nH]1

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.95
MEN1 O00255 2/20 0.95
KMT2A Q03164 2/20 0.95
ALDH1A1 P00352 1/20 0.95
LMNA P02545 1/20 0.95
CYP3A4 P08684 1/20 0.95
NFKB1 P19838 1/20 0.95
VCP P55072 1/20 0.95
SMN1; SMN2 Q16637 1/20 0.95
HIF1A Q16665 1/20 0.95
PDE3A Q14432 1/20 0.73
PNP P00491 6/20 0.67
HBB P68871 2/20 0.67
USP2 O75604 1/20 0.67
TSHR P16473 1/20 0.67
EDNRA P25101 1/20 0.67
HTR2A P28223 1/20 0.67
RECQL P46063 1/20 0.67
HSD17B10 Q99714 1/20 0.67
HPRT1 P00492 6/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ganciclovir SCHEMBL3033 0.98 BLM (1.00) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL2160505 0.98 BLM (1.00) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10481442 0.96 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10901635 0.96 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL11121521 0.96 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL1242615 0.96 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL25915 0.96 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL11093368 0.96 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10481436 0.96 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA
Ganciclovir SCHEMBL10899902 0.96 BLM (0.98) BLMMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102309463-B Ganciclovir tablet composition and preparation method thereof SHANDONG LUOXIN PHARMACY STOCK 2013-02-13 CN disclosed
CN-102309463-A Ganciclovir tablet composition and its preparation method SHANDONG LUOXIN PHARMACY STOCK 2012-01-11 CN disclosed