Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1806983 | 0.99 | KDM4E (0.59) | KDM4EMEN1NPC1POLBMAPT | |
| SCHEMBL10023152 | 0.87 | KDM4E (0.47) | KDM4EMEN1NPC1POLBMAPT | |
| Iodide SCHEMBL7757651 | 0.83 | MEN1 (0.43) | KDM4EMEN1NPC1POLBMAPT | |
| SCHEMBL3931417 | 0.80 | MEN1 (0.39) | KDM4EMEN1NPC1POLBMAPT | |
| SCHEMBL3931412 | 0.80 | MEN1 (0.39) | KDM4EMEN1NPC1POLBMAPT | |
| Iodide SCHEMBL5918845 | 0.79 | MEN1 (0.40) | KDM4EMEN1NPC1POLBMAPT | |
| SCHEMBL12013836 | 0.77 | KDM4E (0.49) | KDM4EMEN1NPC1POLBMAPT | |
| SCHEMBL14984136 | 0.76 | KDM4E (0.44) | KDM4EMEN1NPC1POLBMAPT | |
| SCHEMBL13052541 | 0.76 | MEN1 (0.41) | KDM4EMEN1NPC1POLBMAPT | |
| SCHEMBL14984135 | 0.75 | KDM4E (0.40) | KDM4EMEN1NPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10988810-B2 | Methods and materials for detection of mutations | PENTABASE APS (DK) | 2021-04-27 | — | — | US | disclosed |
| US-20190085400-A1 | METHODS AND MATERIALS FOR DETECTION OF MUTATIONS | PENTABASE APS (DK) | 2019-03-21 | — | — | US | disclosed |
| EP-2004847-B1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2017-05-03 | — | — | EP | disclosed |
| WO-2017045689-A1 | METHODS AND MATERIALS FOR DETECTION OF MUTATIONS | PENTABASE APS (DK) | 2017-03-23 | — | — | WO | disclosed |
| US-8173445-B1 | DNA intercalating agents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-8133984-B2 | Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids | PENTABASE APS (DK) | 2012-03-13 | — | — | US | disclosed |
| US-8133984-B2 | Oligonucleotides comprising signalling pairs and hydrophobic nucleotides, stemless beacons, for detection of nucleic acids, methylation status and mutants of nucleic acids | PENTABASE APS (DK) | 2012-03-13 | — | — | US | disclosed |
| US-20100068704-A1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2010-03-18 | — | — | US | disclosed |
| US-20100068704-A1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2010-03-18 | — | — | US | disclosed |
| US-7462468-B1 | DNA intercalating agents and methods of use | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| US-7297517-B2 | Oligonucleotides and method for detection of meca gene of methicillin-resistant Staphylococcus aureus | TOSOH CORPORATION (JP) | 2007-11-20 | — | — | US | disclosed |
| EP-1792897-A2 | Intercalators having affinity for DNA and methods of use | Abbott Laboratories (US) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068704-A1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | DNMT1, DNMT3A, DNMT3L | KDM4E 4552/4885MEN1 1810/4885NPC1 1858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.