Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 11/20 | 0.33 |
| ▸ | ACHE | P22303 | 11/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984135 | 0.85 | KDM4E (0.40) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL13052541 | 0.82 | MEN1 (0.41) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL3937983 | 0.77 | NPC1 (0.44) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL3937994 | 0.77 | NPC1 (0.44) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| Iodide SCHEMBL5918621 | 0.77 | MEN1 (0.46) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| Iodide SCHEMBL5918618 | 0.77 | MEN1 (0.46) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL278447 | 0.76 | KDM4E (0.57) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| Iodide SCHEMBL1806983 | 0.75 | KDM4E (0.59) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10023152 | 0.68 | KDM4E (0.47) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10023149 | 0.67 | KDM4E (0.48) | KDM4EMEN1ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280921-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. (US) | 2016-09-29 | — | — | US | disclosed |
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137112-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | CRYAA, CRYAB, HSPH1 | KDM4E 4633/4885MEN1 3941/4885ALDH1A1 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.