Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 14/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27844997 | 0.88 | BRAF (0.57) | BRAFMAPK14KDRCA9TRPV1 | |
| SCHEMBL27862187 | 0.84 | KDR (0.43) | BRAFMAPK14KDRCA9CCNC | |
| SCHEMBL27862530 | 0.84 | BRAF (0.54) | BRAFMAPK14KDRCA9CCNC | |
| SCHEMBL14147199 | 0.83 | BRAF (0.55) | BRAFMAPK14KDRCCNCCDK8 | |
| SCHEMBL14146747 | 0.82 | BRAF (0.62) | BRAFMAPK14KDRCA9 | |
| SCHEMBL27862197 | 0.81 | BRAF (0.55) | BRAFMAPK14KDRTRPV1 | |
| SCHEMBL27844947 | 0.81 | BRAF (0.53) | BRAFMAPK14KDRTRPV1 | |
| SCHEMBL27844943 | 0.81 | BRAF (0.56) | BRAFMAPK14KDR | |
| SCHEMBL28796317 | 0.81 | BRAF (0.53) | BRAFMAPK14KDRCA9CCNC | |
| SCHEMBL27862531 | 0.80 | BRAF (0.52) | BRAFMAPK14KDRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250065-A | Substituted triazine phenyl urea derivatives and application thereof | ZHEJIANG HISUN PHARM CO LTD | 2011-11-23 | — | — | CN | disclosed |