Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | BRAF | P15056 | 8/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27844962 | 0.84 | BRAF (0.53) | KDRBRAFCA9CCNCCDK8 | |
| SCHEMBL27845065 | 0.84 | BRAF (0.45) | KDRBRAFEPHX2CA9CCNC | |
| SCHEMBL14146761 | 0.83 | BRAF (0.58) | KDRBRAFEPHX2CA9MAPK14 | |
| SCHEMBL27862281 | 0.82 | BRAF (0.45) | KDRBRAFEPHX2TRPV1MAPK14 | |
| SCHEMBL28796270 | 0.82 | BRAF (0.46) | KDRBRAFEPHX2CA9CCNC | |
| SCHEMBL27845059 | 0.81 | BRAF (0.44) | KDRBRAFEPHX2CA9CCNC | |
| SCHEMBL27844960 | 0.81 | CCR2 (0.46) | KDRBRAFEPHX2CA9CCNC | |
| SCHEMBL27862198 | 0.80 | BRAF (0.43) | KDRBRAFEPHX2CCNCCDK8 | |
| SCHEMBL27844969 | 0.79 | BRAF (0.45) | KDRBRAFEPHX2CCNCCDK8 | |
| SCHEMBL27862533 | 0.79 | FAAH (0.46) | KDRBRAFTRPV1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250065-A | Substituted triazine phenyl urea derivatives and application thereof | ZHEJIANG HISUN PHARM CO LTD | 2011-11-23 | — | — | CN | disclosed |