Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.59 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | FNTA | P49354 | 4/20 | 0.49 |
| ▸ | FNTB | P49356 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391659 | 0.81 | GABBR2 (0.79) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL7995264 | 0.81 | GABBR2 (0.63) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL824927 | 0.81 | GABBR2 (0.63) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL28014207 | 0.79 | GABBR2 (0.76) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL27671897 | 0.79 | GABBR2 (0.65) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL13524865 | 0.77 | GABBR2 (0.58) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL15405894 | 0.76 | GABBR2 (0.71) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL9076600 | 0.76 | GABBR2 (0.71) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL7525502 | 0.76 | GABBR2 (0.71) | GABBR2GABBR1CYP2C9LMNACYP2D6 | |
| SCHEMBL341098 | 0.76 | GABBR2 (0.60) | GABBR2GABBR1CYP2C9LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341099-A | Sustained release oral dosage forms of an R-baclofen prodrug | XENOPORT INC | 2012-02-01 | — | — | CN | claimed |
| CN-102341099-A | Sustained release oral dosage forms of an R-baclofen prodrug | XENOPORT INC | 2012-02-01 | — | — | CN | disclosed |