SCHEMBL278452

SCHEMBL278452

O=C1NCCN1C(O)CO

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PER2 O15055 3/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
RET P07949 1/20 0.32
KDR P35968 1/20 0.32
FAAH O00519 1/20 0.32
NAAA Q02083 1/20 0.32
CRY2 Q49AN0 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5569564 0.78
SCHEMBL29237864 0.74 TOP2A (0.36) PER2ALDH1A1POLBRETKDR
SCHEMBL367449 0.74
SCHEMBL21711063 0.72 ALDH1A1 (0.37) PER2ALDH1A1POLBFAAHNAAA
SCHEMBL10885533 0.72 ALDH1A1 (0.33) PER2ALDH1A1POLBFAAHNAAA
SCHEMBL16029023 0.72 FAAH (0.32) FAAHNAAANPSR1
SCHEMBL8419203 0.71 TOP2A (0.38) PER2ALDH1A1POLBFAAHNAAA
SCHEMBL10434747 0.71 ALDH1A1 (0.33) PER2ALDH1A1POLBNPSR1
SCHEMBL4905970 0.69 ALDH1A1 (0.32) ALDH1A1POLB
SCHEMBL11739284 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120309246-A1 CURABLE BIOPOLYMER NANOPARTICLE LATEX BINDER FOR MINERAL, NATURAL ORGANIC, OR SYNTHETIC FIBER PRODUCTS AND NON-WOVEN MATS ECOSYNTHETIX LTD. 2012-12-06 US disclosed
US-8133952-B2 Poly (vinyl alcohol)—based formaldehyde-free curable aqueous composition DYNEA OY (FI) 2012-03-13 US disclosed
US-7863395-B2 Polyacrylamide-based strengthening agent GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-01-04 US disclosed
WO-2008079531-A2 POLYACRYLAMIDE-BASED STRENGTHENING AGENT GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-07-03 WO disclosed
US-20080149287-A1 POLYACRYLAMIDE-BASED STRENGTHENING AGENT GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-06-26 US disclosed
US-20060252855-A1 Poly (vinyl alcohol) - based formaldehyde-free curable aqueous composition DYNEA AUSTRIA GMBH (AT) 2006-11-09 US disclosed
US-7119148-B2 Glyoxylated polyacrylamide composition strengthening agent GEORGIA-PACIFIC RESINS, INC. (US) 2006-10-10 US disclosed
US-20050187356-A1 Glyoxylated polyacrylamide composition strengthening agent GEORGIA-PACIFIC RESINS, INC. (US) 2005-08-25 US disclosed
US-5147908-A Blend with blocked glyoxal resin and cationic polymer SEQUA CHEMICALS INC. (US) 1992-09-15 US disclosed
EP-0028204-B1 PRE-EXTENDED ETHERIFIED AMINOPLAST RESINS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN SURFACE COATINGS CIBA-GEIGY AG (CH) 1984-02-29 EP disclosed