Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728935 | 0.77 | SCD (0.58) | — | |
| SCHEMBL2525460 | 0.75 | GRIN2D (0.48) | TRPV1AKR1C3TTRRBP4DRD4 | |
| SCHEMBL2524744 | 0.75 | TRPV1 (0.47) | TRPV1AKR1C3TTRRBP4DRD4 | |
| SCHEMBL28796450 | 0.74 | SMN1; SMN2 (0.49) | AKR1C3PHGDHSMN1; SMN2KDM4E | |
| SCHEMBL8805429 | 0.74 | MAPT (0.49) | DRD4GAANPC1RAB9AHTT | |
| SCHEMBL3422227 | 0.74 | AKR1C3 (0.46) | TRPV1AKR1C3TTRRBP4 | |
| SCHEMBL27846243 | 0.73 | ALDH1A1 (0.52) | PHGDHGAAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL23211918 | 0.71 | AKR1C3 (0.54) | TRPV1AKR1C3TTRRBP4DRD4 | |
| SCHEMBL2067822 | 0.71 | MAPT (0.36) | NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL22669019 | 0.71 | AKR1C3 (0.54) | TRPV1AKR1C3TTRRBP4DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102245024-A | Inhibitors of diacylglycerol aclytransferase | VIA PHARMACEUTICALS INC | 2011-11-16 | — | — | CN | disclosed |