Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796506 | 0.85 | DAPK3 (0.51) | FGFR1FGFR3PLK4CHEK1AURKA | |
| SCHEMBL12496411 | 0.83 | MAPK14 (0.60) | MEN1MAPTKMT2ATDP1MAPK14 | |
| SCHEMBL2847216 | 0.82 | IKBKB (0.49) | IKBKBFGFR1FGFR3CDK2CSNK1D | |
| SCHEMBL12496517 | 0.78 | MAPK14 (0.61) | PLK4AURKADAPK3CHEK2CDK1 | |
| SCHEMBL1825175 | 0.77 | MAPK14 (0.60) | PLK4AURKADAPK3CHEK2CDK1 | |
| SCHEMBL11521978 | 0.74 | HSD17B1 (0.58) | MEN1MAPTKMT2ATDP1CYP1A2 | |
| SCHEMBL11525349 | 0.74 | HSD17B1 (0.58) | MEN1MAPTKMT2ATDP1CYP1A2 | |
| SCHEMBL119652 | 0.74 | HSD17B1 (0.58) | MEN1MAPTKMT2ATDP1CYP1A2 | |
| SCHEMBL2841884 | 0.74 | CSNK1A1 (0.46) | IKBKBDAPK3PIM1PRKACAFLT1 | |
| SCHEMBL6692978 | 0.74 | MAPT (0.51) | AKT1PLK1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102256969-A | Compounds that modulate intracellular calcium | CALCIMEDICA INC | 2011-11-23 | — | — | CN | disclosed |