Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580577 | 1.00 | MCHR1 (0.52) | MCHR1L3MBTL3KDM1AMAOAMAOB | |
| SCHEMBL27824379 | 1.00 | MCHR1 (0.52) | MCHR1L3MBTL3KDM1AMAOAMAOB | |
| SCHEMBL4190945 | 0.88 | MAPT (0.53) | MCHR1L3MBTL3HRH3 | |
| SCHEMBL4194751 | 0.88 | MCHR1 (0.48) | MCHR1L3MBTL3KDM1AMAOAMAOB | |
| SCHEMBL27781047 | 0.86 | L3MBTL3 (0.60) | MCHR1L3MBTL3KDM1AMAOAMAOB | |
| SCHEMBL2883532 | 0.85 | L3MBTL3 (0.50) | MCHR1L3MBTL3KDM1AMAOAMAOB | |
| SCHEMBL21464535 | 0.85 | L3MBTL3 (0.50) | MCHR1L3MBTL3KDM1AMAOAMAOB | |
| SCHEMBL2883536 | 0.85 | L3MBTL3 (0.50) | MCHR1L3MBTL3KDM1AMAOAMAOB | |
| SCHEMBL1196740 | 0.85 | L3MBTL3 (0.50) | MCHR1L3MBTL3KDM1AMAOAMAOB | |
| SCHEMBL8159119 | 0.85 | L3MBTL3 (0.50) | MCHR1L3MBTL3KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793248-B | Phthalazinone derivatives and process for preparing the same | 日东制药株式会社 | 2019-08-16 | — | — | CN | disclosed |
| CN-105294655-B | The compound and application thereof of CDK type small molecular inhibitor | 广东东阳光药业有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-105793248-A | Novel phthalazinone derivatives and process for preparing the same | 日东制药株式会社 | 2016-07-20 | — | — | CN | disclosed |
| CN-105294655-A | CDK small-molecule inhibitor compounds and application therefore | GUANGDONG HEC PHARMACEUTICAL | 2016-02-03 | — | — | CN | disclosed |
| CN-103492389-A | Pyrazolo [4, 3-d] pyrimidines useful as kinase inhibitors | ORIGENIS GMBH | 2014-01-01 | — | — | CN | disclosed |
| CN-101796055-B | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE INC | 2013-09-04 | — | — | CN | disclosed |
| CN-102264721-A | Compounds useful as inhibitors of ATR kinase | — | 2011-11-30 | — | — | CN | disclosed |