Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21464535 | 1.00 | L3MBTL3 (0.50) | L3MBTL3KDM1AMAOAMAOBMCHR1 | |
| SCHEMBL2883532 | 1.00 | L3MBTL3 (0.50) | L3MBTL3KDM1AMAOAMAOBMCHR1 | |
| Hydrochloric Acid SCHEMBL3427002 | 0.98 | L3MBTL3 (0.49) | L3MBTL3KDM1AMAOAMAOBMCHR1 | |
| Hydrochloric Acid SCHEMBL3404368 | 0.98 | L3MBTL3 (0.49) | L3MBTL3KDM1AMAOAMAOBMCHR1 | |
| SCHEMBL4239148 | 0.88 | L3MBTL3 (0.40) | L3MBTL3KDM1AMAOAMAOBMCHR1 | |
| SCHEMBL16570183 | 0.88 | L3MBTL3 (0.40) | L3MBTL3KDM1AMAOAMAOBMCHR1 | |
| SCHEMBL3104303 | 0.87 | L3MBTL3 (0.58) | L3MBTL3KDM1AMAOAMAOBMCHR1 | |
| SCHEMBL27580577 | 0.85 | MCHR1 (0.52) | L3MBTL3KDM1AMAOAMAOBMCHR1 | |
| SCHEMBL27824379 | 0.85 | MCHR1 (0.52) | L3MBTL3KDM1AMAOAMAOBMCHR1 | |
| SCHEMBL27847741 | 0.85 | MCHR1 (0.52) | L3MBTL3KDM1AMAOAMAOBMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| CN-116870016-B | Heteroaromatic compound and medical application thereof | 希格生科（深圳）有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117412981-A | Phosphine oxide derivative and preparation method and application thereof | 希格生科（深圳）有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116870016-A | Heteroaromatic compound and medical application thereof | 希格生科（深圳）有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-115785154-A | Heteroaromatic ring compounds and medical use thereof | 希格生科（深圳）有限公司 | 2023-03-14 | — | — | CN | disclosed |
| WO-2022170952-A1 | POLYCYCLIC PYRIDAZINONE DERIVATIVE SERVING AS SOS1 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州阿尔脉生物科技有限公司 | 2022-08-18 | — | — | WO | disclosed |
| WO-2020061116-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| US-9468635-B2 | Fused ring compound for use as mineralocorticoid receptor antagonist | KBP BIOSCIENCES CO., LTD. (CN) | 2016-10-18 | — | — | US | disclosed |
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | disclosed |
| US-20150126501-A1 | Fused Ring Compound For Use As Mineralocorticoid Receptor Antagonist | NOVO NORDISK A/S (DK) | 2015-05-07 | — | — | US | disclosed |
| US-8258141-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-09-04 | — | — | US | disclosed |
| US-20100286126-A1 | Organic Compounds | NOVARTIS AG (CH) | 2010-11-11 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| CN-101348467-A | Substituted bicyclic derivatives for the treatment of abnormal cell growth | PFIZER (US) | 2009-01-21 | — | — | CN | disclosed |
| EP-2013211-A2 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | Novartis AG (CH) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007121920-A2 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2007-11-01 | — | — | WO | disclosed |
| CN-1330640-C | Substituted bicyclic derivatives for the treatment of abnormal cell growth | PFIZER PROD INC (US) | 2007-08-08 | — | — | CN | disclosed |
| CN-1576275-A | Substituted bicyclic derivatives for the treatment of abnormal cell growth | PFIZER PROD INC (US) | 2005-02-09 | — | — | CN | disclosed |
| EP-1292591-B1 | SUBSTITUTED BICYCLIC DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | PFIZER PROD INC (US) | 2005-02-02 | — | — | EP | disclosed |
| CN-1437594-A | Substituted bicyclic derivatives for the treatment of abnormal cell growth | PFIZER PROD INC (US) | 2003-08-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286126-A1 | Organic Compounds | CYP3A43, SLCO1B3, CYP2C19 | L3MBTL3 2471/4885KDM1A 3294/4885MAOA 454/4885 |
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | SRC, PTK2, FYN | L3MBTL3 3296/4885KDM1A 1585/4885MAOA 2378/4885 |
| US-20150126501-A1 | Fused Ring Compound For Use As Mineralocorticoid Receptor Antagonist | NR3C2, REN, MC2R | L3MBTL3 3196/4885KDM1A 3747/4885MAOA 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.