SCHEMBL2784888

SCHEMBL2784888

O=C1c2ccccc2C(=O)c2cc(S(=O)(=O)O)ccc21.[KH]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ MEN1 O00255 3/20 0.54
▸ MAPT P10636 3/20 0.54
▸ MAPK1 P28482 2/20 0.54
▸ PKM P14618 1/20 0.54
▸ HTT P42858 1/20 0.54
▸ PARG Q86W56 5/20 0.53
▸ PKLR P30613 3/20 0.53
▸ STAT3 P40763 1/20 0.53
▸ BCL2 P10415 1/20 0.52
▸ MCL1 Q07820 1/20 0.52
▸ POLB P06746 2/20 0.49
▸ TTR P02766 1/20 0.48
▸ ELANE P08246 1/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29518398 0.98 KMT2A (0.56) KMT2ASMN1; SMN2MEN1MAPTMAPK1
SCHEMBL28718485 0.98 KMT2A (0.56) KMT2ASMN1; SMN2MEN1MAPTMAPK1
SCHEMBL29536345 0.98 KMT2A (0.56) KMT2ASMN1; SMN2MEN1MAPTMAPK1
SCHEMBL426122 0.98 KMT2A (0.56) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Water SCHEMBL2154885 0.96 KMT2A (0.54) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL7758423 0.96 KMT2A (0.54) KMT2ASMN1; SMN2MEN1MAPTMAPK1
SCHEMBL305526 0.96 KMT2A (0.54) KMT2ASMN1; SMN2MEN1MAPTMAPK1
SCHEMBL21840825 0.96 KMT2A (0.54) KMT2ASMN1; SMN2MEN1MAPTMAPK1
SCHEMBL11327335 0.96 KMT2A (0.54) KMT2ASMN1; SMN2MEN1MAPTMAPK1
SCHEMBL28367626 0.96 KMT2A (0.54) KMT2ASMN1; SMN2MEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107442167-B Catalyst for preparing aromatic polycarboxylic acid by liquid phase oxidation 中国石油化工股份有限公司 2020-05-05 — — CN disclosed
CN-107442167-A Liquid phase oxidation prepares the catalyst used in polycarboxylic aromatic acids 中国石油化工股份有限公司 2017-12-08 — — CN disclosed
EP-2218715-B1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION SUMITOMO SEIKA CHEMICALS (JP) 2017-06-28 — — EP disclosed
CN-101925594-B Photoacid generators and photoreactive compositions SUMITOMO SEIKA CHEMICALS 2013-11-20 — — CN disclosed
US-8216768-B2 Photoacid generator and photoreactive composition SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2012-07-10 — — US disclosed
CN-101925594-A Photoacid generators and photoreactive compositions SUMITOMO SEIKA CHEMICALS 2010-12-22 — — CN disclosed
US-20100233621-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2010-09-16 — — US disclosed
EP-2218715-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION Sumitomo Seika Chemicals CO. LTD. (JP) 2010-08-18 — — EP disclosed
US-3974170-A SULFONATES, SULFINATES MONSANTO COMPANY (US) 1976-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233621-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION ARSA, SULT1A1, CYBA KMT2A 1455/4885SMN1; SMN2 4360/4885MEN1 2034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback