Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 3/20 | 0.54 |
| ▸ | PKLR known ✓ | P30613 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PARG | Q86W56 | 7/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1976333 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL29536345 | 0.98 | KMT2A (0.56) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL28718485 | 0.98 | KMT2A (0.56) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL426122 | 0.98 | KMT2A (0.56) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL29518398 | 0.98 | KMT2A (0.56) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL305526 | 0.96 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL2784888 | 0.96 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL21840825 | 0.96 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL7758423 | 0.96 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| SCHEMBL11327335 | 0.96 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7791984-B2 | Method for forming an apparatus for indicating the passage of time and the formed apparatus | Su, Wei-Fang (TW) | 2010-09-07 | — | — | US | claimed |
| CN-101324530-B | Time history indicating device and forming method thereof | WEIFANG LIN | 2010-07-21 | — | — | CN | claimed |
| CN-101324530-A | Time history indicating device and forming method thereof | WEIFANG LIN (CN) | 2008-12-17 | — | — | CN | claimed |
| US-20080219102-A1 | Apparatus for forming an apparatus for indicating the passage of time and the formed apparatus | Su, Wei-Fang (TW) | 2008-09-11 | — | — | US | claimed |
| US-12447239-B2 | 3D-printed bioresorbable all-polymer composite soft tissue scaffolds | NORTHWESTERN UNIVERSITY (US) | 2025-10-21 | — | — | US | disclosed |
| WO-2025091000-A1 | BIODEGRADABLE NANOCOMPOSITE INK FOR 3D PRINTING RADIOPAQUE SCAFFOLDS | NORTHWESTERN UNIVERSITY (US) | 2025-05-01 | — | — | WO | disclosed |
| US-12214104-B2 | Photo-reactive inks and thermal-curable materials made therefrom | NORTHWESTERN UNIVERSITY (US) | 2025-02-04 | — | — | US | disclosed |
| US-20220133958-A1 | 3D-PRINTED BIORESORBABLE ALL-POLYMER COMPOSITE SOFT TISSUE SCAFFOLDS | NORTHWESTERN UNIVERSITY | 2022-05-05 | — | — | US | disclosed |
| CN-107850810-B | Liquid crystal display element | DIC株式会社 | 2021-06-15 | — | — | CN | disclosed |
| US-20210008246-A1 | PHOTO-REACTIVE INKS AND THERMAL-CURABLE MATERIALS MADE THEREFROM | NORTHWESTERN UNIVERSITY (US) | 2021-01-14 | — | — | US | disclosed |
| WO-2020160077-A1 | 3D-PRINTED BIORESORBABLE ALL-POLYMER COMPOSITE SOFT TISSUE SCAFFOLDS | NORTHWESTERN UNIVERSITY (US) | 2020-08-06 | — | — | WO | disclosed |
| WO-2019055656-A1 | PHOTO-REACTIVE INKS AND THERMAL-CURABLE MATERIALS MADE THEREFROM | NORTHWESTERN UNIVERSITY (US) | 2019-03-21 | — | — | WO | disclosed |
| US-7974157-B2 | Method for forming an apparatus for indicating the passage of time and the formed apparatus | Su, Wei-Fang (TW) | 2011-07-05 | — | — | US | disclosed |
| US-20100275835-A1 | Method for forming an apparatus for indicating the passage of time and the formed apparatus | Wei-Fang Su (TW) | 2010-11-04 | — | — | US | disclosed |
| US-7791984-B2 | Method for forming an apparatus for indicating the passage of time and the formed apparatus | Su, Wei-Fang (TW) | 2010-09-07 | — | — | US | disclosed |
| CN-101324530-B | Time history indicating device and forming method thereof | WEIFANG LIN | 2010-07-21 | — | — | CN | disclosed |
| CN-101324530-A | Time history indicating device and forming method thereof | WEIFANG LIN (CN) | 2008-12-17 | — | — | CN | disclosed |
| US-20080219102-A1 | Apparatus for forming an apparatus for indicating the passage of time and the formed apparatus | Su, Wei-Fang (TW) | 2008-09-11 | — | — | US | disclosed |
| CN-1946898-A | Method for dyeing or printing cellulosic fibre materials with reducible dyes | HUNTSMAN ADV MAT SWITZERLAND (CH) | 2007-04-11 | — | — | CN | disclosed |