Phthalic Acid

Phthalic Acid

SCHEMBL27849166

CCCCOC(=O)c1ccccc1C(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.86
TDP1 Q9NUW8 3/20 0.86
L3MBTL1 Q9Y468 2/20 0.86
CYP3A4 P08684 3/20 0.77
MAPK1 P28482 2/20 0.77
TP53 P04637 1/20 0.77
ALDH1A1 P00352 9/20 0.75
LMNA P02545 1/20 0.75
HSD17B10 Q99714 2/20 0.69
KDM4E B2RXH2 2/20 0.60
POLB P06746 1/20 0.60
CA2 P00918 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibutyl Phthalate SCHEMBL27849163 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL151027 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
Benzene SCHEMBL3679548 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL29649180 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
Dibutyl Phthalate SCHEMBL2220638 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL27687840 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL28435163 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL27708612 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL11206095 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL967665 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110105538-A A kind of sole polyurethane elastomer material 蚌埠星烁新材料科技有限公司 2019-08-09 CN disclosed
CN-105820962-A Acremonium and application thereof 陕西师范大学 2016-08-03 CN disclosed
CN-103249772-A Rubber composition and automobile fuel system part using same TOKAI RUBBER IND LTD 2013-08-14 CN disclosed
CN-102345374-A Double-layer high-filling rigid polyvinyl chloride floor SUZHOU FUTONG PLASTIC & ELECTRIC INDUSTRY CO LTD 2012-02-08 CN disclosed