Benzene

Benzene

SCHEMBL3679548

CCCCOC(=O)c1ccccc1C(=O)O.c1ccccc1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.86
TDP1 Q9NUW8 3/20 0.86
L3MBTL1 Q9Y468 2/20 0.86
CYP3A4 P08684 3/20 0.77
MAPK1 P28482 2/20 0.77
TP53 P04637 1/20 0.77
ALDH1A1 P00352 9/20 0.75
LMNA P02545 1/20 0.75
HSD17B10 Q99714 2/20 0.69
KDM4E B2RXH2 2/20 0.60
POLB P06746 1/20 0.60
CA2 P00918 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibutyl Phthalate SCHEMBL27849163 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL151027 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL29649180 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
Phthalic Acid SCHEMBL27849166 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
Dibutyl Phthalate SCHEMBL2220638 1.00 TSHR (0.86) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL27687840 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL28435163 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL27708612 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL11206095 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1
SCHEMBL967665 0.98 TSHR (0.83) TSHRTDP1L3MBTL1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2891555-B1 HYBRID FLOORING PRODUCTS ARMSTRONG WORLD IND INC (US) 2020-07-29 EP claimed
US-20150224221-A1 METHOD FOR PREPARING MICROSPHERES FOR EMBOLI, AND METHOD FOR PREPARING MICROSPHERES TO WHICH DRUG-CONTAINING CARRIER IS BOUND CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-08-13 US claimed
EP-2891485-A2 METHOD FOR PREPARING MICROSPHERES FOR EMBOLI, AND METHOD FOR PREPARING MICROSPHERES TO WHICH DRUG-CONTAINING CARRIER IS BOUND Chung-Ang University Industry Academic Cooperation Foundation (KR) 2015-07-08 EP claimed
EP-2891555-A1 Hybrid flooring products Armstrong World Industries, Inc. (US) 2015-07-08 EP claimed
US-20150184399-A1 HYBRID FLOORING PRODUCT ARMSTRONG FLOORING, INC. 2015-07-02 US claimed
CN-103450546-A Anti-fogging and non-dropping film and preparation method thereof WUJIANG YINGLIDA PLASTIC PACKAGE CO LTD 2013-12-18 CN claimed
US-5510411-A Flask for microwave processing of dental protheses UNIVERSITY OF PITTSBURGH (US) 1996-04-23 US claimed
US-20250065310-A1 FISCHER TROPSCH CATALYST SYSTEM NEXCERIS INNOVATION HOLDINGS, LLC 2025-02-27 US disclosed
EP-4457302-A1 FISCHER TROPSCH CATALYST SYSTEM NEXCERIS INNOVATION HOLDINGS, LLC (US) 2024-11-06 EP disclosed
CN-118843675-A Fischer-Tropsch catalyst system 奈克斯赛瑞斯创新控股有限责任公司 2024-10-25 CN disclosed
EP-3954399-B1 MICROBEADS FOR EMBOLIZATION AND COMPOSITION FOR TREATING PROLIFERATIVE DISEASES PLMICROMED CO LTD (KR) 2023-11-15 EP disclosed
WO-2023129688-A1 FISCHER TROPSCH CATALYST SYSTEM NEXCERIS INNOVATION HOLDINGS, LLC (US) 2023-07-06 WO disclosed
US-20220370361-A1 MICROBEADS FOR EMBOLIZATION AND COMPOSITION FOR TREATING PROLIFERATIVE DISEASES PLMICROMED CO., LTD. (KR) 2022-11-24 US disclosed
US-20060233955-A1 Process for the coating of metallic components with an aqueous organic composition CHEMETALL GMBH (DE) 2006-10-19 US disclosed
US-6749891-B2 ZINC OXIDE IS SINTERED TO MAKE A VARISTOR ELEMENT, THE VARISTOR ELEMENT IS BURIED INTO A MIXTURE BASED ON SIO2 AND IS SUBJECTED TO HEAT TREATMENT, ZN2SIO4 FILM HAVING ACID AND ALKALI RESISTANCE IS FORMED ON THE SURFACE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-06-15 US disclosed
US-20030043012-A1 Zinc oxide varistor and method of manufacturing same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-03-06 US disclosed
US-20030043013-A1 Zinc oxide varistor and method of manufacturing same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-03-06 US disclosed
EP-1288971-A1 Zinc oxide varistor and method of manufacturing same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-03-05 EP disclosed
US-5510411-A Flask for microwave processing of dental protheses UNIVERSITY OF PITTSBURGH (US) 1996-04-23 US disclosed
US-4224202-A DI- OR TRIMETHACRYLATE CROSSLINKING MONOMER, PROTECTED COBALT CATALYST, POLAR SOLVENT; QUICK-DRYING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220370361-A1 MICROBEADS FOR EMBOLIZATION AND COMPOSITION FOR TREATING PROLIFERATIVE DISEASES MKI67, CD47, TFRC TSHR 595/4885TDP1 4313/4885L3MBTL1 1432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.