Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869168 | 0.86 | ALDH1A1 (0.45) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL18786131 | 0.81 | ALDH1A1 (0.50) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL8276768 | 0.79 | ALDH1A1 (0.45) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL5035092 | 0.79 | ALDH1A1 (0.45) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL868798 | 0.79 | ALDH1A1 (0.45) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL3282371 | 0.73 | ALDH1A1 (0.44) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL14388774 | 0.72 | MITF (0.43) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL11864264 | 0.72 | MITF (0.43) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL11377647 | 0.71 | MITF (0.39) | ALDH1A1PKMSOS1KMT2AMITF | |
| SCHEMBL27996346 | 0.71 | ALDH1A1 (0.38) | ALDH1A1PKMSOS1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541836-A | Prodrug forms of kinase inhibitors and their use in therapy | AUCKLAND UNISERVICES LTD | 2016-05-04 | — | — | CN | disclosed |
| CN-102574846-B | Kinase inhibitors, prodrug forms thereof and their use in therapy | AUCKLAND UNISERVICES LTD | 2014-12-03 | — | — | CN | disclosed |
| CN-102348708-A | Prodrug forms of kinase inhibitors and their use in therapy | AUCKLAND UNISERVICES LTD | 2012-02-08 | — | — | CN | disclosed |