Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419126 | 0.77 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL14377006 | 0.76 | MAPK1 (0.71) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL27885531 | 0.72 | MAPT (0.40) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL28009982 | 0.71 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL23486528 | 0.67 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL10298797 | 0.67 | MAPK1 (0.51) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL3485682 | 0.66 | MAPK1 (1.00) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL19174891 | 0.66 | KDM4E (0.46) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL359075 | 0.65 | MAPK1 (0.66) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL27382017 | 0.65 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MAPK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102388043-A | Histamine h3 inverse agonists and antagonists and methods of use thereof | SEPRACOR INC | 2012-03-21 | — | — | CN | disclosed |