2-Phenylphenol

2-Phenylphenol

SCHEMBL27850752

C/C=C/C=C/C(=O)O.Oc1ccccc1-c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
HPGD P15428 2/20 0.55
BCL2L1 Q07817 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP2C9 P11712 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
NFKB1 P19838 1/20 0.42
CA4 P22748 1/20 0.42
RXRA P19793 1/20 0.40
NR4A2 P43354 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
BACE1 P56817 2/20 0.38
ADAMTS4 O75173 1/20 0.38
ALOX5 P09917 1/20 0.38
HNF4A P41235 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylphenol SCHEMBL11388999 0.98 ALDH1A1 (0.53) ALDH1A1HPGDBCL2L1HSD17B10MEN1
2-Phenylphenol SCHEMBL21325943 0.86 ALDH1A1 (0.50) ALDH1A1HPGDBCL2L1HSD17B10MEN1
Biphenyl SCHEMBL27698809 0.83 MAPT (0.44) ALDH1A1HPGDMEN1KMT2ACYP2C9
2-Phenylphenol SCHEMBL11385741 0.81 ALDH1A1 (0.41) ALDH1A1HPGDBCL2L1HSD17B10MEN1
Sorbic Acid SCHEMBL27150 0.79 CA1 (0.44) ALDH1A1MEN1KMT2ACA1CA2
Sorbic Acid SCHEMBL27542402 0.79 CA1 (0.44) ALDH1A1MEN1KMT2ACA1CA2
Sorbic Acid SCHEMBL27148 0.79 CA1 (0.44) ALDH1A1MEN1KMT2ACA1CA2
Salicylic Acid SCHEMBL7758032 0.79 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10CA1CA2
Salicylic Acid SCHEMBL8598633 0.79 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10CA1CA2
Salicylic Acid SCHEMBL6470180 0.79 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102458374-A Skin delivery compositions comprising active agent-calcium phosphate particle complexes and methods of use thereof LAB SKIN CARE INC 2012-05-16 CN disclosed