Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL8598633 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDCA1CA2 | |
| Salicylic Acid SCHEMBL7758032 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDCA1CA2 | |
| Salicylic Acid SCHEMBL8598638 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDCA1CA2 | |
| Salicylic Acid SCHEMBL28081903 | 0.88 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDCA1CA2 | |
| Methyl Salicylate SCHEMBL27893810 | 0.84 | LMNA (0.65) | ALDH1A1KDM4EHPGDCA1CA2 | |
| Salicylic Acid SCHEMBL240023 | 0.84 | HPGD (0.78) | ALDH1A1KDM4EHPGDCA1CA2 | |
| Salicylic Acid SCHEMBL7299833 | 0.84 | HPGD (0.78) | ALDH1A1KDM4EHPGDCA1CA2 | |
| Salicylic Acid SCHEMBL27652523 | 0.84 | HPGD (0.78) | ALDH1A1KDM4EHPGDCA1CA2 | |
| Salicylic Acid SCHEMBL240025 | 0.84 | HPGD (0.78) | ALDH1A1KDM4EHPGDCA1CA2 | |
| Salicylic Acid SCHEMBL28189208 | 0.82 | ALDH1A1 (0.82) | ALDH1A1KDM4EHPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933046-B1 | Releasable corrosion inhibitor compositions | TDA RESEARCH, INC. (US) | 2005-08-23 | — | — | US | disclosed |
| WO-2001085896-A1 | CONCENTRATE FOR DILUTION WITH MAINTENANCE OF OR AN INCREASE IN VISCOSITY | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-15 | — | — | WO | disclosed |