Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | IL18 | Q14116 | 1/20 | 0.55 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112467 | 0.87 | MAPT (0.68) | SMN1; SMN2RAB9ANPC1MAPTCA2 | |
| SCHEMBL30577265 | 0.86 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL4351643 | 0.84 | MAPT (0.67) | RAB9ANPC1MAPTLMNATSHR | |
| SCHEMBL14433939 | 0.83 | EPHX2 (0.58) | RAB9ANPC1MAPTLMNATSHR | |
| SCHEMBL12584977 | 0.83 | NPC1 (0.77) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL4118302 | 0.83 | NPC1 (0.77) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL4358449 | 0.82 | MAPT (0.69) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL4111390 | 0.81 | SMN1; SMN2 (0.75) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL11054945 | 0.80 | MAPT (0.81) | SMN1; SMN2RAB9AMAPTLMNATSHR | |
| SCHEMBL4110972 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ANPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4431959-B2 | — | — | 2010-03-17 | — | — | JP | claimed |
| US-20080221215-A1 | ANTIVIRAL INHIBITION OF CAPSID PROTEINS | SUMMERS MICHAEL F | 2008-09-11 | — | — | US | claimed |
| EP-1513959-A4 | ANTIVIRAL INHIBITIONS OF CAPSID PROTEINS | UNIV MARYLAND AT BALTIMORE COU (US) | 2008-07-23 | — | — | EP | claimed |
| JP-2005536717-A | — | — | 2005-12-02 | — | — | JP | claimed |
| EP-1513959-A2 | ANTIVIRAL INHIBITIONS OF CAPSID PROTEINS | University of Maryland at Baltimore County (US) | 2005-03-16 | — | — | EP | claimed |
| US-20030228573-A1 | Antiviral inhibition of capsid proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-11 | — | — | US | claimed |
| WO-2003089615-A2 | ANTIVIRAL INHIBITIONS OF CAPSID PROTEINS | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2003-10-30 | — | — | WO | claimed |
| US-20080221215-A1 | ANTIVIRAL INHIBITION OF CAPSID PROTEINS | SUMMERS MICHAEL F | 2008-09-11 | — | — | US | disclosed |
| EP-1513959-A4 | ANTIVIRAL INHIBITIONS OF CAPSID PROTEINS | UNIV MARYLAND AT BALTIMORE COU (US) | 2008-07-23 | — | — | EP | disclosed |
| US-7361459-B2 | Antiviral inhibition of capsid proteins | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2008-04-22 | — | — | US | disclosed |
| EP-1513959-A2 | ANTIVIRAL INHIBITIONS OF CAPSID PROTEINS | University of Maryland at Baltimore County (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20030228573-A1 | Antiviral inhibition of capsid proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-11 | — | — | US | disclosed |
| WO-2003089615-A2 | ANTIVIRAL INHIBITIONS OF CAPSID PROTEINS | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2003-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221215-A1 | ANTIVIRAL INHIBITION OF CAPSID PROTEINS | CAPRIN1, CAPG, NCBP1 | SMN1; SMN2 4006/4885RAB9A 2651/4885NPC1 660/4885 |
| US-20030228573-A1 | Antiviral inhibition of capsid proteins | CAPRIN1, CAPG, NCBP1 | SMN1; SMN2 4006/4885RAB9A 2651/4885NPC1 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.