SCHEMBL5706002

SCHEMBL5706002

O=C(Oc1ccccc1Cl)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.63
MAPT P10636 4/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
SLC6A3 Q01959 1/20 0.56
MEN1 O00255 3/20 0.54
ESR1 P03372 2/20 0.54
ESR2 Q92731 2/20 0.54
HSD17B10 Q99714 2/20 0.54
JAK2 O60674 1/20 0.54
USP2 O75604 1/20 0.54
GAA P10253 1/20 0.54
ALOX15 P16050 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
PTK2B Q14289 1/20 0.54
HPGD P15428 2/20 0.51
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
LMNA P02545 3/20 0.50
F2 P00734 1/20 0.50
METAP2 P50579 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7539631 0.91 HPGD (0.64) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL3149726 0.89 PTK2B (0.51) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL7051957 0.89 PTK2B (0.51) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
Malonic Acid SCHEMBL8953219 0.87 KMT2A (0.50) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL1975083 0.87 HPGD (0.51) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL11330648 0.87 KMT2A (0.58) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL5706048 0.85 SLC6A3 (0.58) KMT2AMAPTSMN1; SMN2SLC6A3PTK2B
SCHEMBL5706143 0.85 ESR1 (0.56) KMT2AMAPTSMN1; SMN2MEN1ESR1
SCHEMBL6939316 0.85 KMT2A (0.56) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL725404 0.85 KMT2A (0.76) KMT2AMAPTSMN1; SMN2SLC6A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101417986-A Method for preparing 2-chlorophenothiazine TAICANG YUNTONG CHEMICAL PLANT (CN) 2009-04-29 CN claimed
CN-119708924-A Ink, ink preparation method and ink-jet printing method 广东聚华印刷显示技术有限公司 2025-03-28 CN disclosed
CN-112110817-B Method for preparing diaryl ester compound by high-efficiency catalysis of palladium pyridine 陕西师范大学 2022-07-26 CN disclosed
CN-112110817-A Method for preparing diaryl ester compound by high-efficiency catalysis of palladium pyridine 陕西师范大学 2020-12-22 CN disclosed
CN-105473548-A Amide derivatives as lysophosphatidic acid receptor antagonists TAKEDA PHARMACEUTICALS CO 2016-04-06 CN disclosed
CN-101417986-A Method for preparing 2-chlorophenothiazine TAICANG YUNTONG CHEMICAL PLANT (CN) 2009-04-29 CN disclosed
CN-101203512-A Heterocyclic compounds DAIICHI SANKYO CO LTD (JP) 2008-06-18 CN disclosed
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-0807255-B1 LIPOSOME-ENHANCED IMMUNOAGGREGATION ASSAY AND TEST DEVICE CORNELL RES FOUNDATION INC (US) 2005-12-21 EP disclosed
CN-1216052-C Anti-neurodegeneratively active 10-aminoaliphatyl-dibenz (b,f) oxepines NAVARTIS AG (CH) 2005-08-24 CN disclosed
US-4563512-A AROMATIC ESTER AND ALIPHATIC ETHER OR TERTIARY AMINE SHELL OIL COMPANY (US) 1986-01-07 US disclosed
EP-0155716-A1 Olefin polymerization process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-09-25 EP disclosed
US-4490513-A COORDINATION CATALYST; ORGANOMAGNESIUM COMPOUND; ORGANIC SILICON COMPOUND; ESTER; TITANIUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-12-25 US disclosed
US-4479138-A PHENYL BENZOIC ESTER TO INCREASE SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1984-10-23 US disclosed
US-4259225-A STORAGE STABILITY DAINIPPON INK & CHEMICALS, INC. (JP) 1981-03-31 US disclosed
US-4232139-A Process for producing polymers or copolymers of olefins containing at least 3 carbon atoms MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1980-11-04 US disclosed
US-4143223-A TITANIUM, HALOGEN, ALUMINUM, ESTER AND AN ALCOHOL MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1979-03-06 US disclosed
US-4069169-A TITANIUM TETRAHALIDE, BENZOIC ACID ESTER DERIVATIVES MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1978-01-17 US disclosed
US-4026798-A PROLONGING USE FMC CORPORATION (US) 1977-05-31 US disclosed
US-4013575-A Dry cleaning with peracids FMC CORPORATION (US) 1977-03-22 US disclosed