Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814775 | 0.83 | GAA (0.67) | GAANPC1RAB9AALDH1A1NPY2R | |
| SCHEMBL9542280 | 0.80 | NPC1 (0.62) | GAANPC1RAB9AALDH1A1NPY2R | |
| SCHEMBL10089213 | 0.80 | GAA (0.70) | GAANPC1RAB9ANPY2RMGLL | |
| SCHEMBL8844508 | 0.80 | NPC1 (0.69) | GAANPC1RAB9AALDH1A1NPY2R | |
| SCHEMBL12474605 | 0.79 | GAA (0.68) | GAANPC1RAB9AALDH1A1NPY2R | |
| SCHEMBL13677251 | 0.78 | GAA (0.63) | GAANPC1RAB9AALDH1A1NPY2R | |
| SCHEMBL470967 | 0.78 | GAA (1.00) | GAANPC1RAB9AALDH1A1NPY2R | |
| SCHEMBL9542192 | 0.78 | GAA (0.75) | GAANPC1RAB9AALDH1A1NPY2R | |
| SCHEMBL14389792 | 0.78 | GAA (0.67) | GAANPC1RAB9ANPY2R | |
| SCHEMBL3900599 | 0.78 | GAA (0.76) | GAANPC1RAB9AALDH1A1NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015697-B | Amide derivatives and pharmaceutical compositions containing the same | DAINIPPON SUMITOMO PHARMA CO | 2015-06-17 | — | — | CN | disclosed |
| CN-102015697-A | Amide derivatives and pharmaceutical compositions containing the same | DAINIPPON SUMITOMO PHARMA CO | 2011-04-13 | — | — | CN | disclosed |