Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852443 | 0.90 | TSHR (0.43) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL3785359 | 0.76 | ALDH1A1 (0.46) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL27869331 | 0.70 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1TSHRCYP2C19 | |
| SCHEMBL24318061 | 0.69 | KDM4E (0.51) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL28797481 | 0.68 | SLC6A2 (0.43) | KDM4EKMT2AALDH1A1TSHRCYP1A2 | |
| SCHEMBL27852493 | 0.66 | BACE1 (0.38) | KMT2AMEN1ALDH1A1TSHRPOLB | |
| SCHEMBL3777633 | 0.66 | ALDH1A1 (0.48) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9128468 | 0.66 | ALDH1A1 (0.54) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL32687865 | 0.66 | ALDH1A1 (0.54) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL14193348 | 0.64 | TSHR (0.54) | KDM4EKMT2AMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101415677-B | Method for producing polycyclic lactams | SUMITOMO CHEMICAL CO | 2012-05-23 | — | — | CN | disclosed |