Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27869391 | 0.83 | TAAR1 (0.40) | HSD17B10KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL3781516 | 0.77 | KMT2A (0.46) | SLC6A2SLC6A4CYP1A2MAPK1KMT2A | |
| SCHEMBL3772459 | 0.75 | CYP1A2 (0.45) | SLC6A2SLC6A4HSD17B10CYP1A2MAPK1 | |
| SCHEMBL27869331 | 0.70 | ALDH1A1 (0.39) | HSD17B10TSHRCYP3A4CYP2D6MAPK1 | |
| SCHEMBL3787457 | 0.69 | MMP2 (0.44) | HSD17B10CYP1A2KMT2AALDH1A1MAPT | |
| SCHEMBL23022877 | 0.68 | CTSK (0.47) | SLC6A2SLC6A4KMT2ACTSKKDM4E | |
| SCHEMBL27852525 | 0.68 | KDM4E (0.45) | TSHRCYP1A2MAPK1KMT2AKDM4E | |
| SCHEMBL30472636 | 0.68 | SLC6A2 (0.40) | SLC6A2SLC6A4CYP3A4ALDH1A1NPSR1 | |
| SCHEMBL1934486 | 0.68 | SLC6A2 (0.40) | SLC6A2SLC6A4CYP3A4ALDH1A1NPSR1 | |
| SCHEMBL2295236 | 0.68 | SLC6A2 (0.40) | SLC6A2SLC6A4CYP3A4ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101415677-B | Method for producing polycyclic lactams | SUMITOMO CHEMICAL CO | 2012-05-23 | — | — | CN | disclosed |