Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009407 | 0.86 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2KDM4EKDM2BKMT2A | |
| SCHEMBL17320112 | 0.86 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2KDM4EKDM2BKMT2A | |
| SCHEMBL1817113 | 0.86 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2KDM4EKDM2BKMT2A | |
| SCHEMBL7314623 | 0.85 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4EKDM2BKMT2A | |
| SCHEMBL28107109 | 0.85 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4EKDM2BKMT2A | |
| SCHEMBL28107477 | 0.85 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4EKDM2BKMT2A | |
| SCHEMBL27358578 | 0.82 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL14556078 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4EKDM2BKMT2A | |
| SCHEMBL952722 | 0.81 | LTA4H (0.63) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL952721 | 0.81 | LTA4H (0.63) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015712-A | Heterocyclic compounds as adenosine receptor antagonist | ADVINUS THERAPEUTICS PVT LTD | 2011-04-13 | — | — | CN | disclosed |