Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4529502 | 0.94 | SYK (0.34) | GAAMGAMSIMGAM2NLRP3 | |
| SCHEMBL4529505 | 0.86 | ALDH1A1 (0.33) | NLRP3MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL27725685 | 0.83 | GAA (0.38) | GAAKMT2AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL27725680 | 0.77 | TDP1 (0.33) | GAAMEN1KMT2AHPGDMAPT | |
| SCHEMBL28794883 | 0.74 | MGAM (0.47) | GAAMGAMSIMGAM2NLRP3 | |
| SCHEMBL10132033 | 0.73 | MAPK1 (0.44) | NLRP3PKMSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL21652667 | 0.71 | MGAM (0.62) | GAAMGAMSIMGAM2NLRP3 | |
| SCHEMBL30585693 | 0.70 | MEN1 (0.47) | GAAMGAMSIMGAM2NLRP3 | |
| SCHEMBL2094172 | 0.70 | MEN1 (0.47) | GAAMGAMSIMGAM2NLRP3 | |
| Malonic Acid Diethyl Ester SCHEMBL10896529 | 0.70 | GAA (0.94) | GAAMGAMSIMGAM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101326176-B | Pyridazine compound and use thereof | SUMITOMO CHEMICAL CO | 2012-05-30 | — | — | CN | disclosed |