Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535342 | 0.88 | CHRNB2 (0.34) | GAAMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL2848902 | 0.81 | KDM4E (0.44) | GAACASP1MEN1HPGDKMT2A | |
| SCHEMBL27870438 | 0.81 | GAA (0.46) | MGAMGAASIMGAM2PKM | |
| SCHEMBL4535346 | 0.80 | SMN1; SMN2 (0.34) | GAAMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27746548 | 0.79 | ALDH1A1 (0.38) | GAAKMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL15863371 | 0.76 | MGAM (0.44) | MGAMGAASIMGAM2PKM | |
| SCHEMBL28773546 | 0.76 | TDP1 (0.36) | GAAPKMCASP1MEN1HPGD | |
| SCHEMBL27870422 | 0.75 | L3MBTL1 (0.48) | MGAMGAASIMGAM2HPGD | |
| SCHEMBL27853643 | 0.74 | GAA (0.46) | MGAMGAASIMGAM2PKM | |
| SCHEMBL27853660 | 0.73 | GAA (0.54) | MGAMGAASIMGAM2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101326176-B | Pyridazine compound and use thereof | SUMITOMO CHEMICAL CO | 2012-05-30 | — | — | CN | disclosed |