Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ANPEP | P15144 | 4/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1364077 | 0.75 | HDAC1 (0.61) | ALDH1A1EPHX2MAPT | |
| SCHEMBL6407136 | 0.72 | F7 (0.64) | F7ATML3MBTL1ANPEPKLKB1 | |
| SCHEMBL5158191 | 0.72 | F7 (0.55) | F7ALDH1A1EPHX2MAPTKMT2A | |
| SCHEMBL5158199 | 0.72 | F7 (0.55) | F7ALDH1A1EPHX2MAPTKMT2A | |
| SCHEMBL27537790 | 0.72 | NPC1 (0.59) | L3MBTL1ALDH1A1EPHX2MAPT | |
| SCHEMBL14575948 | 0.71 | PPIB (0.62) | ATML3MBTL1ANPEPKLKB1ALDH1A1 | |
| SCHEMBL14576521 | 0.71 | PPID (0.53) | ATMANPEPKMT2APOLB | |
| SCHEMBL8550262 | 0.70 | NPC1 (0.53) | ALDH1A1EPHX2 | |
| SCHEMBL5160205 | 0.68 | F7 (0.59) | F7ANPEPKLKB1ALDH1A1KMT2A | |
| SCHEMBL1365408 | 0.68 | HDAC1 (0.58) | ALDH1A1EPHX2MAPTKMT2ANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258677-A2 | Histone deacetylase inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2010-12-08 | — | — | EP | disclosed |