Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.64 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 6/20 | 0.53 |
| ▸ | FCER2 | P06734 | 5/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160205 | 0.87 | F7 (0.59) | F7MMP8ANPEPALDH1A1KMT2A | |
| SCHEMBL6411176 | 0.85 | F7 (0.57) | F7MMP8ALDH1A1KMT2AMMP1 | |
| SCHEMBL6407898 | 0.83 | F7 (0.55) | F7MMP8ANPEPALDH1A1KMT2A | |
| SCHEMBL6410493 | 0.83 | MMP1 (0.57) | F7ALDH1A1KMT2AMMP1 | |
| SCHEMBL5158191 | 0.82 | F7 (0.55) | F7MMP8ALDH1A1KMT2A | |
| SCHEMBL5158199 | 0.82 | F7 (0.55) | F7MMP8ALDH1A1KMT2A | |
| SCHEMBL6407102 | 0.80 | F7 (0.52) | F7MMP8ANPEPALDH1A1KMT2A | |
| SCHEMBL4418014 | 0.79 | F7 (1.00) | F7ANPEPMMP1KLKB1 | |
| SCHEMBL6409719 | 0.79 | F7 (0.51) | F7ANPEPALDH1A1KMT2AMMP1 | |
| SCHEMBL23529664 | 0.79 | CTSS (0.64) | MMP8KMT2AATMCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277690-A1 | Small molecules for treatment of hypercholesterolemia and related diseases | AVANIR PHARMACEUTICALS | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277690-A1 | Small molecules for treatment of hypercholesterolemia and related diseases | LDLR, NPC1L1, CETP | F7 4389/4885MMP8 3190/4885ANPEP 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.