Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CDC25C | P30307 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771444 | 0.90 | SMPD1 (0.42) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2773020 | 0.90 | KMT2A (0.43) | PSMD14MMP2BLMMEN1KMT2A | |
| SCHEMBL2770600 | 0.90 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2791143 | 0.89 | DHODH (0.42) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2772268 | 0.89 | KMT2A (0.44) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2773803 | 0.88 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2785396 | 0.86 | KDM4E (0.42) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2785822 | 0.86 | PDE4B (0.41) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2787046 | 0.85 | PTGES (0.40) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2788405 | 0.84 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |