Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598271 | 0.89 | LMNA (0.59) | TSHRKMT2AMEN1LMNAGAA | |
| SCHEMBL3876644 | 0.84 | KMT2A (0.62) | TSHRKMT2AMEN1TRPV1LMNA | |
| SCHEMBL4340762 | 0.84 | TSHR (0.59) | TSHRKMT2AMEN1TRPV1LMNA | |
| SCHEMBL29177251 | 0.83 | MEN1 (0.47) | TSHRKMT2AMEN1CA12CA1 | |
| SCHEMBL29010952 | 0.83 | CA12 (0.53) | TSHRKMT2AMEN1NPC1PKM | |
| SCHEMBL27909784 | 0.79 | TRPV1 (0.54) | TSHRKMT2AMEN1TRPV1LMNA | |
| SCHEMBL14959931 | 0.79 | KDM4E (0.61) | TSHRKMT2AMEN1TRPV1LMNA | |
| SCHEMBL14959934 | 0.79 | KDM4E (0.61) | TSHRKMT2AMEN1TRPV1LMNA | |
| SCHEMBL7318359 | 0.79 | LMNA (0.51) | TSHRKMT2AMEN1TRPV1LMNA | |
| SCHEMBL15091861 | 0.78 | KMT2A (0.51) | TSHRKMT2AMEN1TRPV1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015698-A | Oxazolidinone derivatives | ACTELION PHARMACEUTICALS LTD | 2011-04-13 | — | — | CN | disclosed |