Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12216197 | 0.90 | LMNA (0.56) | TRPV1TSHRLMNAGAARAB9A | |
| SCHEMBL28643781 | 0.83 | GRM5 (0.42) | TRPV1TSHRKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4340762 | 0.81 | TSHR (0.59) | TRPV1TSHRLMNAGAARAB9A | |
| SCHEMBL3876644 | 0.81 | KMT2A (0.62) | TRPV1TSHRLMNAGAARAB9A | |
| SCHEMBL12216202 | 0.80 | CTNNB1 (0.45) | TRPV1KMT2AKDM4ESMN1; SMN2POLB | |
| SCHEMBL27854530 | 0.79 | TSHR (0.56) | TRPV1TSHRLMNAGAARAB9A | |
| SCHEMBL12216209 | 0.79 | GRM5 (0.51) | TRPV1RAB9AKMT2ANPC1MAOB | |
| SCHEMBL14959931 | 0.77 | KDM4E (0.61) | TRPV1TSHRLMNAGAARAB9A | |
| SCHEMBL14959934 | 0.77 | KDM4E (0.61) | TRPV1TSHRLMNAGAARAB9A | |
| SCHEMBL10512935 | 0.77 | TYMS (0.43) | LMNAKMT2APKMMEN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201279-A | Compounds useful as modulators of TRPM8 | SENOMYX INC | 2013-07-10 | — | — | CN | disclosed |