Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287364 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4ECASP1CYP1A2CYP2D6 | |
| SCHEMBL27854946 | 0.74 | ALDH1A1 (0.48) | ALDH1A1KDM4ECASP1CYP1A2CYP2D6 | |
| SCHEMBL287351 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KDM4ECASP1CYP1A2CYP2D6 | |
| SCHEMBL27871680 | 0.69 | ALDH1A1 (0.39) | ALDH1A1KDM4ECASP1KMT2AMAPT | |
| SCHEMBL8247021 | 0.65 | KMT2A (0.62) | ALDH1A1CYP1A2CYP2D6KMT2ALMNA | |
| SCHEMBL287300 | 0.63 | ALDH1A1 (0.48) | ALDH1A1KDM4ECASP1KMT2AMAPT | |
| SCHEMBL7357067 | 0.63 | SLC6A1 (0.69) | ALDH1A1CYP1A2CYP2D6LMNATSHR | |
| SCHEMBL5164434 | 0.62 | SLC6A1 (0.78) | ALDH1A1CYP1A2CYP2D6LMNATSHR | |
| SCHEMBL10968404 | 0.62 | SLC6A1 (0.78) | ALDH1A1CYP1A2CYP2D6LMNATSHR | |
| SCHEMBL5164435 | 0.62 | SLC6A1 (0.78) | ALDH1A1CYP1A2CYP2D6LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459175-A | Piperidine derivatives for the treatment of diabetes | TORRENT PHARMACEUTICALS LTD | 2012-05-16 | — | — | CN | claimed |
| CN-102459175-A | Piperidine derivatives for the treatment of diabetes | TORRENT PHARMACEUTICALS LTD | 2012-05-16 | — | — | CN | disclosed |