SCHEMBL27855165

SCHEMBL27855165

CNc1cc(OCc2ccccc2C(O)C(N)=O)cc(NC)c1NC

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.38
PARP10 Q53GL7 6/20 0.34
PARP15 Q460N3 3/20 0.34
MAOB P27338 3/20 0.34
PARP14 Q460N5 2/20 0.34
IKBKB O14920 1/20 0.34
SCN3A Q9NY46 2/20 0.33
CD274 Q9NZQ7 1/20 0.33
HIF1A Q16665 1/20 0.33
FABP4 P15090 1/20 0.33
FABP5 Q01469 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
TMPRSS6 Q8IU80 1/20 0.33
ST14 Q9Y5Y6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27940488 0.88 KCNH2 (0.35) MAOBHIF1AFABP4FABP5
SCHEMBL15375503 0.83 CD274 (0.44) SCN9APARP10PARP15MAOBPARP14
SCHEMBL27952264 0.82 FABP4 (0.38) SCN9APARP10PARP15PARP14SCN3A
SCHEMBL28809569 0.82 FABP4 (0.38) SCN9APARP10PARP15MAOBPARP14
SCHEMBL15375385 0.81 PARP10 (0.42) SCN9APARP10PARP15MAOBPARP14
SCHEMBL27952263 0.80 CD274 (0.34) CD274KDM4E
SCHEMBL15375524 0.79 KDM4E (0.50) SCN9APARP10PARP15MAOBPARP14
SCHEMBL28038430 0.79 FABP4 (0.36) PARP10PARP15MAOBPARP14CD274
SCHEMBL15375571 0.77 PARP10 (0.47) SCN9APARP10PARP15MAOBPARP14
SCHEMBL15375555 0.77 SMN1; SMN2 (0.44) MAOBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
CN-102348677-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2012-02-08 CN disclosed