SCHEMBL28038430

SCHEMBL28038430

CNC(=O)C(OC)c1ccccc1COc1cc(NC)c(NC)c(NC)c1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.36
FABP5 Q01469 1/20 0.36
HIF1A Q16665 2/20 0.34
LMNA P02545 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CD274 Q9NZQ7 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 2/20 0.32
POLB P06746 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MAOB P27338 1/20 0.32
FFAR1 O14842 1/20 0.31
PARP10 Q53GL7 2/20 0.31
PARP15 Q460N3 1/20 0.31
PARP14 Q460N5 1/20 0.31
LTA4H P09960 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27940488 0.86 KCNH2 (0.35) FABP4FABP5HIF1AMEN1KMT2A
SCHEMBL15402296 0.85 ALDH1A1 (0.40) FABP4FABP5LMNAMEN1KMT2A
SCHEMBL15401968 0.85 LMNA (0.41) FABP4FABP5LMNACD274POLB
SCHEMBL15375322 0.84 FABP4 (0.44) FABP4FABP5LMNAMEN1KMT2A
SCHEMBL28038428 0.83 FABP4 (0.42) FABP4FABP5LMNAKMT2AALDH1A1
SCHEMBL28038429 0.83 FABP4 (0.42) FABP4FABP5LMNAMEN1KMT2A
SCHEMBL15402061 0.81 MEN1 (0.44) FABP4FABP5LMNAMEN1KMT2A
SCHEMBL15402468 0.81 SMN1; SMN2 (0.45) MEN1KMT2AMAOB
SCHEMBL27855165 0.79 SCN9A (0.38) FABP4FABP5HIF1ACD274KDM4E
SCHEMBL15402114 0.79 RAB9A (0.44) MEN1KMT2AALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed