Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228847 | 0.75 | DRD3 (0.39) | DRD3GRM5 | |
| SCHEMBL2276782 | 0.69 | NPC1 (0.41) | DRD3LMNAGRM5 | |
| SCHEMBL15939245 | 0.69 | DRD3 (0.39) | DRD3LMNAGRM5 | |
| SCHEMBL11357704 | 0.67 | — | — | |
| SCHEMBL2227755 | 0.67 | KMT2A (0.41) | DRD3LMNAGRM5 | |
| SCHEMBL17207711 | 0.67 | DRD3 (0.46) | DRD3 | |
| SCHEMBL17002563 | 0.65 | DRD3 (0.47) | DRD3LMNA | |
| SCHEMBL820287 | 0.64 | DRD3 (0.46) | DRD3 | |
| SCHEMBL14808858 | 0.64 | — | — | |
| SCHEMBL21047642 | 0.64 | SMYD3 (0.38) | LMNACYP1A2CYP2D6SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102361887-A | Polymers functionalized with nitrile compounds containing a protected amino group | BRIDGESTONE CORP | 2012-02-22 | — | — | CN | disclosed |