Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229883 | 0.86 | KMT2A (0.40) | KMT2ALMNAADORA3ADORA1CYP3A4 | |
| SCHEMBL2227867 | 0.73 | BRD4 (0.43) | KMT2ALMNAADORA3ADORA1CYP3A4 | |
| SCHEMBL2229020 | 0.71 | KMT2A (0.41) | KMT2ALMNACYP3A4TSHRALDH1A1 | |
| SCHEMBL2229081 | 0.68 | MAPT (0.35) | KMT2ALMNATSHRALDH1A1GAA | |
| SCHEMBL27855262 | 0.67 | DRD3 (0.44) | DRD3GRM5LMNA | |
| SCHEMBL6901376 | 0.63 | ALDH1A1 (0.44) | KMT2ATSHRALDH1A1GAAMAPT | |
| SCHEMBL150590 | 0.62 | DRD3 (0.53) | DRD3GRM5CYP3A4 | |
| SCHEMBL2228847 | 0.62 | DRD3 (0.39) | DRD3GRM5 | |
| SCHEMBL151486 | 0.61 | DRD3 (0.62) | KMT2ADRD3TSHRALDH1A1 | |
| SCHEMBL20552309 | 0.61 | TSHR (0.49) | TSHRHSD17B10ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |